PRP ntseeg tau li cas?
PRP ua los ntawm degranulation ntawm alpha hais hauv platelets, uas muaj qee yam kev loj hlob.PRP yuav tsum tau npaj nyob rau hauv lub xeev anticoagulant thiab yuav tsum tau siv nyob rau hauv grafts, flaps, los yog qhov txhab nyob rau hauv 10 feeb ntawm cov ntshav txhaws.
Raws li cov platelets tau qhib los ntawm cov txheej txheem ntawm cov txheej txheem, cov txheej txheem loj hlob yog secreted los ntawm cov cell los ntawm cov cell membrane.Hauv cov txheej txheem no, alpha particles fuse rau platelet cell membranes, thiab cov protein loj hlob tuaj ua tiav lub xeev bioactive los ntawm kev ntxiv histone thiab carbohydrate sab chains rau cov proteins.
Cov kev tshawb fawb tau pom tias cov neeg laus mesenchymal qia hlwb, osteoblasts, fibroblasts, endothelial hlwb, thiab epidermal hlwb qhia cell membrane receptors rau kev loj hlob yam hauv PRP.Cov transmembrane receptors nyob rau hauv lem induce lub activation ntawm endogenous internal signaling proteins uas ua rau cov kev qhia (xauv) ntawm ib txwm cellular gene sequences, xws li cell proliferation, matrix tsim, osteoid tsim, collagen synthesis, thiab lwm yam.
Yog li, PRP txoj kev loj hlob yam tsis tau nkag mus rau hauv lub xov tooj ntawm tes lossis nws cov nucleus, lawv tsis yog mutagenic, lawv tsuas yog ua kom lub zog ntawm kev kho kom zoo.
Tom qab thawj zaug tawg ntawm PRP-txuas nrog kev loj hlob yam, platelets synthesize thiab secrete ntxiv kev loj hlob yam tseem ceeb rau 7 hnub ntawm lawv lub neej.Thaum platelets depleted thiab tuag, macrophages uas ncav cuag thaj av los ntawm platelet-stimulated cov hlab ntsha loj hlob mus rau hauv lub luag hauj lwm ntawm lub qhov txhab kho regulator los ntawm secreting ib co ntawm cov tib txoj kev loj hlob yam tseem ceeb thiab lwm yam.Yog li, tus naj npawb ntawm cov platelets nyob rau hauv graft, qhov txhab, los yog cov ntshav txhaws nyob rau hauv lub flap txiav txim seb lub qhov txhab kho sai npaum li cas.PRP tsuas yog ntxiv rau tus lej ntawd.
1) PRP tuaj yeem txhim kho cov pob txha progenitor hlwb hauv cov pob txha thiab cov pob txha grafts thiab txhawb kev tsim cov pob txha.PRP tseem muaj ntau yam kev loj hlob, uas tuaj yeem txhawb kev faib tawm ntawm tes thiab kev sib txawv thiab txhawb kev kho lub cev.
2) Leukocytes hauv PRP tuaj yeem txhim kho qhov muaj peev xwm tiv thaiv kab mob ntawm qhov chaw raug mob, pab lub cev tshem tawm cov ntaub so ntswg necrotic, thiab ua kom kho qhov raug mob.
3) PRP muaj ntau cov fibrin, uas tuaj yeem tsim kho kom zoo dua qub rau kev kho lub cev thiab ntsws qhov txhab tib lub sijhawm.
PRP puas muaj kev nyab xeeb thiab siv tau tiag?
1) Autologous cov khoom siv ntshav
Ntau qhov kev sim cov ntaub ntawv tau pom tias PRP tuaj yeem pom nws txoj kev nyab xeeb thiab kev ntseeg siab hauv ntau yam kev kho mob.Raws li cov khoom siv ntshav autologous, PRP zoo zam kev tsis lees paub thiab kev kis kab mob los ntawm kev siv cov ntshav allogeneic thaum kho.
2) Coagulation pib muaj kev nyab xeeb
PRP siv bovine thrombin ua tus coagulation pib, ua rau tib lub sijhawm PRP rho tawm thiab cov txheej txheem phais.Lub bovine thrombin siv yog ua kom sov thiab tsis ua rau mob.Thiab vim hais tias tus nqi ntawm bovine thrombin siv tsawg heev, nws tsis nkag mus rau hauv lub cev thiab ua rau tsis lees paub thaum siv.
3) Cov khoom muaj kev nyab xeeb thiab siv tau zoo
Cov txheej txheem aseptic yog siv rau hauv kev npaj PRP, ua rau cov ntshav txhaws tsis ua rau muaj kab mob thiab tsis ua rau cov kab mob loj hlob.
(Cov ntsiab lus ntawm tsab xov xwm no tau luam tawm dua, thiab peb tsis muab ib qho kev qhia lossis kev lees paub rau qhov raug, kev ntseeg tau lossis ua tiav ntawm cov ntsiab lus muaj nyob rau hauv tsab xov xwm no, thiab tsis muaj lub luag haujlwm rau cov kev xav ntawm tsab xov xwm no, thov nkag siab.)
Post lub sij hawm: Sep-14-2022